How environmental constraints influence the dynamics of a population and its evolution
Wolfram head the pleasure to present at the Quantitative Methods in Gene Regulation V meeting in London. Many exciting talks at the interface of physics and biology!
Our new preprint The collective effect of finite-sized inhomogeneities on the spatial spread of populations in two dimensions is available on arXiv.
Lucy and Thomas joined the group and started their PhD work! Welcome to the group!
About the Lab
We are interested in how the physical world shapes the dynamics in biological systems. We currently focus on the role of the environment on the evolutionary dynamics of populations expanding into new habitats.
We use a variety of models, mostly borrowed from physics, simulation techniques and protocols necessary to make quantitative measurements. Our current model system of choice is bacteriophage T7 spreading on a lawn of the bacterium E. coli.
Möbius W*, Tesser F*, Alards KMJ, Benzi R, Nelson DR, and Toschi F. (2019)
The collective effect of finite-sized inhomogeneities on the spatial spread of populations in two dimensions, arXiv:1910.05332.
* Authors contributed equally.
Beller DA, Alards KMJ, Tesser F, Mosna RA, Toschi F, and Möbius W, Evolution of populations expanding on curved surfaces, EPL, 2018.
Chacón JM, Möbius W, and Harcombe WR, The spatial and metabolic basis of colony size variation, ISME J, 2018.
Weinstein BT, Lavrentovich MO, Möbius W, Murray AW, and Nelson DR, Genetic drift and selection in many-allele range expansions, PLoS Computational Biology, 2017.